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Structures of NS5 Methyltransferase from Zika Virus.

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To aid in the development of antivirals, we present two high-resolution…
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Structural basis of Zika virus helicase in recognizing its substrates

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The ZIKV helicase, which plays a pivotal role in viral RNA…
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Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

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ZIKV relies on its NS2B/NS3 protease for polyprotein processing;…
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Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

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Zika virus (ZIKV) is responsible for a major ongoing epidemic…
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A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

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Currently there are no approved vaccines or specific therapies…
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Neuroteratogenic Viruses and Lessons for Zika Virus Models

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The Centers for Disease Control and Prevention has confirmed…
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Structural Basis of Zika Virus-Specific Antibody Protection

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Zika virus (ZIKV) infection during pregnancy has emerged as a…
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Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission

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Zika virus (ZIKV) infection during pregnancy is linked to severe…
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The green tea molecule EGCG inhibits Zika virus entry

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During ZIKV the outbreak in Brazil it was observed an increase…
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Zika infection may be worse in people already exposed to a common virus

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A previous encounter with a disease that is rampant across…
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OpenZika Principal Investigator, Dr. Carolina Horta Andrade,…
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Structural basis of potent Zika-dengue virus antibody cross-neutralization.

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Zika virus is related to dengue virus, and we report here that…
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Extended Surface for Membrane Association in Zika Virus NS1 Structure

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A high-resolution (1.89 Å) crystal structure of  NS1 protein…
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Structure of the NS3 helicase from Zika virus (French Polynesia strain)

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Zika virus has emerged as a pathogen of major health concern.…
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Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

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In order to elucidate the molecular basis of this hyper-activity,…
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A Method to Detect Zika-Blocking Bacteria

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A growing body of research suggests infections with the Wolbachia…
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France's Sanofi partners U.S. Army to speed up Zika vaccine

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French drugmaker Sanofi said on Wednesday it had struck a research…
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Sex May Spread Zika Virus More Often Than Researchers Suspected

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An outbreak of the Zika virus in the continental United States…
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Pathology of congenital Zika syndrome in Brazil: a case series

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Viral antigens were localised to glial cells and neurons and…
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Vaccine protection against Zika virus from Brazil

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Here we show that a single immunization of a plasmid DNA vaccine…
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Study: Zika virus infections last longer during pregnancy

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University of Wisconsin-Madison researchers studying monkeys…
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Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

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Here we investigated the serological cross-reaction between…
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Zika Virus in the Human Placenta and Developing Brain: Cell Tropism and Drug Inhibition

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Here, we identify the placental and brain cell populations…
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Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

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The flaviviruses dengue virus (DENV) and Zika virus (ZIKV)…
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Scientists use CRISPR to discover Zika and dengue weaknesses

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Scientists from Washington have discovered human proteins that…
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Uveitis Associated with Zika Virus Infection

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 We report on a man in his early 40s who had an unremarkable…
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Scientists announce important Zika milestone: First vaccine ready for human trials

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Pennsylvania vaccine maker Inovio Pharmaceuticals and South…
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Zika virus at the Olympic games: is it safe?

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In a notorious scene in the film Marathon Man, a runner (played…