Uveitis Associated with Zika Virus Infection

 We report on a man in his early 40s who had an unremarkable medical history and a 2-day history of a rash and bilateral ocular hyperemia. ZIKV infection was diagnosed by means of a positive real-time reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assay of a serum specimen. A peripheral-blood sample was also positive for anti-ZIKV IgM antibodies detected by means of an in-house enzyme-linked immunosorbent assay and a plaque-reduction neutralization test (titer, 1:5000).We suspect that some persons with a diagnosis of ZIKV-related conjunctivitis may have intraocular inflammation. Uveitis may be a potential manifestation of ZIKV infection.

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