Notícias – Página: 19

Combating Zika virus

maio 11, 2016/0 Comentários/em Notícias /por melina

To stop the spread of Zika and prevent other infectious disease outbreaks,USAID launched Combating Zika and Future Threats: A Grand Challenge for Development. The challenge calls upon the global innovator community to generate cutting-edge approaches to fight the current Zika outbreak and to help strengthen the world’s response to infectious diseases in the future.

Combating Zika | Grand Challenge for Development | U.S. Agency for International Development

Last updated: May 11, 2016

To stop the spread of Zika and prevent other infectious disease outbreaks, USAID launched Combating Zika and Future Threats: A Grand Challenge for Development. USAID is calling for the global innovator community to generate cutting-edge technologies and approaches to fight Zika in the near term and to help strengthen the world’s response to infectious diseases in the future.

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Adding Zika Virus to the FDA Priority Review Voucher Program Act

maio 11, 2016/0 Comentários/em Notícias /por melina

This bill amends the Federal Food, Drug, and Cosmetic Act to add the Zika virus to the list of tropical diseases under the priority review voucher program, which awards a voucher to the sponsor of a new drug or biological product that is approved to prevent or treat a tropical disease. (A voucher entitles the holder to have a future new drug or biological product application acted upon by the Food and Drug Administration within six months.)

114th Congress (2015-2016): Adding Zika Virus to the FDA Priority Review Voucher Program Act | Congress.gov | Library of Congress

Zika Virus Vaccine Programme

maio 11, 2016/0 Comentários/em Notícias /por melina

A new Zika vaccine based on a simian adenoviral vector is being developed in Oxford to determine if it is immunogenic and can be taken to clinical trials. This development is part of a global rapid response programme.

May 11, 2016

Zika Virus Vaccine Programme – Jenner Institute

jenner

Zika vaccine efficacy trials could start in 2017

maio 10, 2016/0 Comentários/em Notícias /por rodolphobraga

In the most optimistic scenario, a Zika vaccine could prove its worth by the start of 2018, Anthony Fauci, head of the U.S. National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland, said today.

Zika vaccine efficacy trials could start in 2017 | Science | AAAS

Zika virus animation

maio 10, 2016/0 Comentários/em Notícias /por melina

The model of Zika virus is a part of the non-commercial educational project Viral Park, which was launched by the Visual Science in 2009. The project includes models of HIV, influenza A/H1N1, adenovirus, Ebola and papilloma viruses. Models and visualizations of the Viral Park received Science Magazine and National Science Foundation awards, appeared on the cover of Nature Medicine special issue, were published in the NY Times, Vaccines textbook, Cell journal Picture Show and were included into presentations of the Nobel Prize winners. The Viral Park models are made in atomic resolution, and are built based on the latest scientific data and computational biology simulations. The models sum up all the available information about the structure of the most widespread and dangerous human viruses and may act as a stand-alone scientific reviews in a graphical form.

March 10, 2016

The history of Zika virus

maio 9, 2016/0 Comentários/em Notícias /por melina

A chronological map of the presence of Zika only in those countries for which there is evidence of indigenous transmission by mosquitos, excluding the many countries that have notified imported Zika. infections.

The following timeline summarizes the spread of Zika infection, country by country, from the earliest discovery in 1947 to the latest information as of 7 February 2016. Zika virus infection appears to have changed in character while expanding its geographical range.

May 9, 2016

WHO | The History of Zika Virus

africa-zika-timeline

Projeto vai mapear resposta imunológica humana contra o Zika

maio 9, 2016/0 Comentários/em Notícias /por rodolphobraga

Pesquisadores brasileiros, ingleses e norte-americanos uniram forças em um projeto que tem como objetivo mapear a resposta imunológica humana contra o vírus Zika. Os resultados poderão servir de base, no futuro, para o desenvolvimento de uma vacina.

Projeto vai mapear resposta imunológica humana contra o Zika | AGÊNCIA FAPESP

09 de maio de 2016

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ZIKV h9 organoid graphicalabstract 26Apr16_JD

Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3

maio 7, 2016/0 Comentários/em Notícias /por melina

Here we show that a prototype strain of ZIKV, MR766, efficiently infects organoids and causes a decrease in overall organoid size that correlates with the kinetics of viral copy number. The innate immune receptor Toll-like-Receptor 3 (TLR3) was upregulated after ZIKV infection of human organoids and mouse neurospheres and TLR3 inhibition reduced the phenotypic effects of ZIKV infection.

May 7, 2016

Medicamento antimalárico dá resultado contra Zika

maio 7, 2016/0 Comentários/em Notícias /por melina

Medicamento já usado contra malária pode ser capaz de blindar o cérebro dos fetos contra a infecção por vírus Zika.

Remédio antimalária dá resultado contra zika – Saúde – Estadão

06 de maio de 2016

cloroquina

O medicamento, cloroquina, protegeu neurosferas, estruturas celulares que reproduzem o cérebro em formação, em até 95%

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Wolbachia Blocks Currently Circulating Zika Virus Isolates in Brazilian Aedes aegypti Mosquitoes

maio 5, 2016/0 Comentários/em Notícias /por melina

The recent association of Zika virus with cases of microcephaly has sparked a global health crisis and highlighted the need for mechanisms to combat the Zika vector, Aedes aegyptimosquitoes. Wolbachia pipientis, a bacterial endosymbiont of insect, has recently garnered attention as a mechanism for arbovirus control. Here we report that Aedes aegypti harboringWolbachia are highly resistant to infection with two currently circulating Zika virus isolates from the recent Brazilian epidemic. Wolbachia-harboring mosquitoes displayed lower viral prevalence and intensity and decreased disseminated infection and, critically, did not carry infectious virus in the saliva, suggesting that viral transmission was blocked. Our data indicate that the use of Wolbachia-harboring mosquitoes could represent an effective mechanism to reduce Zika virus transmission and should be included as part of Zika control strategies.

May 5, 2016