Zika Virus and Birth Defects — Reviewing the Evidence for Causality

On the basis of this review, we conclude that a causal relationship exists between prenatal Zika virus infection and microcephaly and other serious brain anomalies.

April 14, 2016



Fiocruz promove seminários discutindo controle, atenção e vigilância dos vírus Zika, Dengue e Chikungunya


Illustrating and homology modeling the proteins of the Zika virus

Several suggested steps have been proposed which could be taken to initiate ZIKV antiviral drug discovery using both high throughput screens as well as structure-based design based on homology models for the key proteins. We now describe preliminary homology models created for NS5, FtsJ, NS4B, NS4A, HELICc, DEXDc, peptidase S7, NS2B, NS2A, NS1, E stem, glycoprotein M, propeptide, capsid and glycoprotein E using SWISS-MODEL.

May 5, 2016

Illustrating and homology modeling the proteins of the Zika virus – F1000Research




Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome. Because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillain-Barré syndrome.

May 1, 2016


Figure: Weekly cases of suspected Zika virus infections and Guillain-Barré syndrome in French Polynesia between October, 2013, and April, 2014